The influence of cement replacement by fly ash in brick masonry strength was experimentally verified in the paper. The obtained results have shown that the replacement in rich in cement mortars is possible up to 40%, without unfavorable effect on mortars properties. However, this replacement can have unfavorable influence on mortar strength in the case of leaner cement mortars and the replacement in these mortars must be limited and hence the fly ash addition may not be useful. The use of high strength bricks allows the use of mortar mixes with higher level of cement replacement by fly ash as well ias n rich and lean mixes. A minimum 20% of cement can be replaced by fly ash. The use of high strength bricks in combination with rich mortar mixes the cement can be replaced with fly ash to the maximum extent, without affecting the strength of brick masonry. In this case the replacement can be about 40 %. The application of fly ash in masonry has a very favorable effect on environment because it is a useful developed of this waste.