Design and calculation of building sound performance is standardized in EN 12354. The calculation method of this relatively new standard requires a lot of precise input data. Besides the mass per area of a massive component, values like the vibration reduction index and the loss factor are required. As a consequence of the implementation of EN 12354, plenty of research was initiated about the acoustic properties of different construction materials. In collaboration with different research institutes and Universities numerous measurements on AAC structures were performed. The results have become the basis for the integration of the EN 12354 into the German standard DIN 4109. Based on the experience gained in applying the calculation method of EN 12354-1, this paper gives an overview about the acoustic performance of single leaf AAC structures in comparison with other building materials. The sound reduction indices of pure materials as AAC, lightweight concrete or calcium silicate bricks are compared. In a second step, the calculated sound reduction indices are compared with measurement results of real buildings. It could be confi rmed, that the determined sound reduction indices in planning of a building are in suffi cient agreement with the measured and quantifi ed sound insulation in the real building. It is concluded that there is a good correlation between calculated performance on the basis of the material parameters, and the actual measured sound performance for AAC structures. This proves a high level of certainty in achieving the required sound insulation in design and construction of AAC buildings.